Abstract:
Neisseria gonorrhoeae, an organism which previously was
found to be extremely sensitive to penicillin and other
antibiotics is becoming increasingly resistant. As
penicillin is still used in many areas as first line
antibiotic therapy for the treatment of gonorrhoea it has
become imperative to draw attention to this fact.
This study demonstrates the appearance of resistant
Neisseria gonorrhoeae strains in Bloemfontein and the
dramatic increase in these strains. The mechanisms of
resistance are demonstrated as well as the role which is
played by the alteration of penicillin binding proteins.
