DSpace Repository

Perioperative Blood Loss in South African Primary Hip Arthroplasty Patients

Show simple item record

dc.contributor.author Khattab, Mohamed S.
dc.contributor.author Moodley, Yoshan
dc.date.accessioned 2021-01-17T13:14:52Z
dc.date.available 2021-01-17T13:14:52Z
dc.date.issued 2019
dc.identifier.uri http://hdl.handle.net/11462/2162
dc.description Primary Research en_US
dc.description.abstract Background: Perioperative blood loss in South African (SA) primary hip arthroplasty patients has not been described. This information could improve patient management during the perioperative period in this setting. Our study objectives were to 1) determine perioperative blood loss in SA primary hip arthroplasty patients, and 2) determine which characteristics are associated with major perioperative blood loss in SA primary hip arthroplasty patients. Methods: This was a retrospective cohort study of 174 patients who underwent primary hip arthroplasty over a 22-month period at the Inkosi Albert Luthuli Hospital, SA. All patients were part of a pre-existing registry. Data for each patient included: Age, gender, anthropometric measurements, comorbidity, orthopaedic variables, laboratory test results, American Society of Anesthesiologists Score, general anaesthesia, duration of surgery, preoperative tranexamic acid, postoperative thromboprophylaxis, and perioperative blood transfusion. Estimated perioperative blood loss (in mL) was calculated using the Gross Equation. Minimum, maximum, mean, and median perioperative blood loss were calculated. Major perioperative blood loss was defined as an estimated perioperative blood loss which was >75th percentile obtained for the study sample. Data were analyzed using appropriate methods. Results: Perioperative blood loss ranged from 10.3 mL to 3041.8 mL. Mean perioperative blood loss was 1103.1 ± 556.2 mL. Median perioperative blood loss was 1008.8 mL, with an interquartile range of 706.2–1357.0 mL. Independent statistical associations were observed between major perioperative blood loss and the following characteristics: chronic obstructive pulmonary disease (OR: 3.01, 95% CI: 1.01–8.95; p=0.048), preoperative tranexamic acid (OR: 0.28, 95% CI: 0.13–0.63; p=0.002), and perioperative blood transfusion (OR: 10.18, 95% CI: 3.53–29.34; p<0.001). Conclusion: The levels of perioperative blood loss observed in our sample of SA primary hip arthroplasty patients are consistent with the range of estimated blood loss reported in the published literature for hip arthroplasty populations in other countries. SA primary hip arthroplasty patients who suffer major perioperative blood loss are more likely to have COPD or require perioperative blood transfusion. Preoperative tranexamic acid was protective against major perioperative blood loss. en_US
dc.language.iso en en_US
dc.publisher University of Toronto Medical Journal en_US
dc.relation.ispartofseries UTMJ;• Volume 96, Number 3, June 2019 : Cannabis
dc.title Perioperative Blood Loss in South African Primary Hip Arthroplasty Patients en_US
dc.type Article en_US

Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


My Account