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Browsing Research Articles: Faculty of Health and Environmental Sciences by Author

Browsing Research Articles: Faculty of Health and Environmental Sciences by Author "Mashele, Samson Sitheni"

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Antimicrobial activity screening of Philenoptera violacea (Klotzsch) schrire and Xanthocercis zambesiaca (Baker) Dumaz-Le-Grand

Mfengwana, Polo-Ma-Abiele Hildah; Mashele, Samson Sitheni (J. Pharm. Sci. & Res., 2016)

Microorganism involvement in cancer has been identified for over a century, and different types of bacteria have been associated with carcinogenesis. Philenoptera violacea (Klotzsch) Schrire and Xanthocercis zambesiaca ...
Comparative analysis of P450 signature motifs EXXR and CXG in the large and diverse kingdom of fungi: identification of evolutionarily conserved amino acid patterns characteristic of P450 family

Syed, Khajamohiddin; Mashele, Samson Sitheni (PLoS One, 2014)

Cytochrome P450 monooxygenases (P450s) are heme-thiolate proteins distributed across the biological kingdoms. P450s are catalytically versatile and play key roles in organisms primary and secondary metabolism. Identification ...
Comparative Genomics and Evolutionary Analysis of Cytochrome P450 Monooxygenases in Fungal Subphylum Saccharomycotina

Kgosiemang, Ipeleng Kopano Rosinah; Mashele, Samson Sitheni; Syed, Khajamohiddin (JOURNAL OF PURE & APPLIED MICROBIOLOGY, 2014)

Cytochrome P450 monooxygenases (P450s) are heme-thiolate enzymes and play an important role in the primary and secondary metabolism of living organisms. Genome sequencing analysis of fungal organisms revealed the presence ...
Cytochrome P450 monooxygenase analysis in free-living and symbiotic microalgae Coccomyxa sp. C-169 and Chlorella sp. NC64A

Mthakathi, Ntsane Trevor; Kgosiemang, Ipeleng Kopano Rosinah; Chen, Wanping; Mohlatsane, Molikeng Eric; Mojahi, Thebeyapelo Jacob; Yu, Jae-Hyuk; Mashele, Samson Sitheni; Syed, Khajamohiddin (Algae, 2015)

Microalgae research is gaining momentum because of their potential biotechnological applications, including the generation of biofuels. Genome sequencing analysis of two model microalgal species, polar free-living Coccomyxa ...
Cytochrome P450 Monooxygenase CYP53 Family in Fungi: Comparative Structural and Evolutionary Analysis and Its Role as a Common Alternative Anti-Fungal Drug Target

Jawallapersand, Poojah; Mashele, Samson Sitheni; Kovacic, Lidija; Stojan, Jure; Komel, Radovan; Pakala, Suresh Babu; Krasevec, Nada; Syed, Khajamohiddin (PLOS, 2014)

Cytochrome P450 monooxygenases (CYPs/P450s) are heme-thiolate proteins whose role as a drug target against pathogenic microbes has been explored because of their stereo- and regio-specific oxidation activity. We aimed to ...
Genome-Wide Annotation and Comparative Analysis of Cytochrome P450 Monooxygenases in Basidiomycete Biotrophic Plant Pathogens

Qhanya, Lehlohonolo Benedict; Matowane, Godfrey; Chen, Wanping; Sun, Yuxin; Letsimo, Elizabeth Mpholoseng; Parvez, Mohammad; Yu, Jae-Hyuk; Mashele, Samson Sitheni; Syed, Khajamohiddin (Journal PLOS ONE, 2015)

Fungi are an exceptional source of diverse and novel cytochrome P450 monooxygenases (P450s), heme-thiolate proteins, with catalytic versatility. Agaricomycotina saprophytes have yielded most of the available information ...
Genome-wide identification, annotation and characterization of novel thermostable cytochrome P450 monooxygenases from the thermophilic biomass-degrading fungi Thielavia terrestris and Myceliophthora thermophila

Syed, Khajamohiddin; Shale, Karabo; Nazir, K. H. M. Nazmul Hussain; Krasevec, Nada; Mashele, Samson Sitheni; Pagadala, Nataraj Sekhar (Genes & Genomics, 2014)

Cytochrome P450 monooxygenases (P450s) are ubiquitous heme-thiolate proteins that have potential biotechnological application. Thermostable-P450s that can withstand hostile industrial conditions, such as high ...

Browsing Research Articles: Faculty of Health and Environmental Sciences by Author "Mashele, Samson Sitheni"

Browsing Research Articles: Faculty of Health and Environmental Sciences by Author "Mashele, Samson Sitheni"

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